Hi SingerSongwriter,
Genos has no built-in USB-AUDIO Interface. You can use the USB-to-Host connection to the computer only for USB-MIDI.
When using with Windows, and the Yamaha USB-MIDI Driver is installed on the PC, you have one USB-MIDI OUT Port (Transmit) and two USB-MIDI IN Ports (Receive) for the Genos.
If you want to use the MIC Effects and/or the Vocal Harmony of the Genos, you can route the MIC to two of the SUB Line Outs, e.g. SUB 1 & 2. All other Parts are output on the MAIN Line Outs (L and R) then as usual. To record the MIC and the other Parts simultaneously on you DAW, you need an Audio Interface with at least 4 Line Inputs. Your "Scarlett 6i6" is suitable for this.
If you don't use the MIC Effects and/or the VH of the Genos, you can connect your Mic directly to one of the XLR Inputs of the Scarlett of course (and use the Effects from the DAW for the MIC).
I hope I got your question right ...
P.S.
All Line Outputs of the Genos are unbalanced. So you have to use standard TS cables for the connection to your Audio Interface. (Do NOT use balanced TRS cables!)
Best regards,
Chris