Lots of things can be saved into registration files. That is one of great advantages of using them.
Just press the 'memory' button to the right of the registration buttons and you will see a screen where you can choose what to save into a registration button. (press esc to remove the screen after you had a look).
The problem is that, when fiddling around with third party registration files, you do not know what was saved in them. So just loading one can change things you may not be aware of at the moment of change, but that you will only discover in weeks or maybe in months. Such thing can be button assignments, live control settings, audio out settings ..... In your case, the pedal settings were changed, maybe others too.
As Fred suggested you can use the freeze function to avoid changes, but that works selectively. You have to freeze what you don't want to change, which is not allways predictable
Some consider it good practice, when you have your Genos set up as you want it, to save everything (check all the options you see when pressing the memory buton) into a registrationfile and call it Master Configuration or something. So that after trying out third party registrations, even if you do not notice anything strange, you can load your master configuration registration before continuing so that you are sure, you Genos is unchanged.
Unfortunatly I do not exactly understand your problem, so I cannot offer any help there.
But maybe the above advice may help you avoid those kind of problems in the future.
Best of luck!
Best Regards
Rudy